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This sebum, primarily composed of triglycerides, wax esters, squalene, and free fatty acids, normally plays a protective role as part of the hydrolipid film that maintains the hydration and suppleness of the epidermis

These factors include haem oxygenase-1, which has important anti-inflammatory properties toward cytokines including upregulating IL-10, and downregulating IL-6 and TNF through other means, such as NF-B signalling

In this 2024 randomized controlled trial, researchers tested the impact of L-theanine (200 mg) and L-tyrosine (2000 mg) on stress markers and cognitive performance during a high-stress scenario

10.1016/S0891-5849(02)01357-6 18 BentingerM.TekleM.DallnerG

Lillehoj H, Liu Y, Calsamiglia S, Fernandez-Miyakawa ME, Chi F, Cravens RL, Oh S, Gay CG