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Varied uptake Penetration was very high in some markets (particularly Latin America which boasts all 5 of the top 5 markets for percentage share of capsule consumption) and substantial in larger markets such as Japan, UK, and South Korea (8%, 8%, and 6%, respectively) but much lower to negligible penetration in very large markets such as Russia, Indonesia, and China mean that at a global level the category is still niche

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In 2023, Friends star Matthew Perry drowned in a hot tub after using the drug