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Department of Health and Social Care and NHS England

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10 The underlying mechanisms likely involve diverse constituents of smoke, including nicotine, oxygen free radicals, and carbon monoxide, which may affect various targets, such as the mucus layer, gut microbiota, immune cells, gastrointestinal motility, and microvasculature

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However, many cities including Austin, Houston, Dallas, San Antonio, and El Paso have passed their own smoke-free ordinances that prohibit indoor smoking in public places and workplaces