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Flavor molecules, reacting with the propylene glycol in the e-liquid, can produce metabolites, or intermediate substances that are part of metabolic reactions, that are irritating to the respiratory system

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They could suffer withdrawal symptoms like nervousness, irritability, anxiety, and difficulty concentrating

And this despite the fact that smoking still represents the greatest threat to human health, directly causing 93,000 more deaths than alcohol, drugs, road accidents, AIDS, homicide and suicide combined