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A vitamin B12 deficiency may be the cause

For adults over 50, B12 supplementation is crucial for maintaining clear eyesight and preventing AMD progression

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(20) These are not the only reasons that glutathione levels could be insufficient

A Cochrane review from 2013 pooled data from six RCTs of NAC or carbocysteine (another mucolytic) in children with respiratory infections and found some benefit, although it was deemed to be of limited clinical relevance