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Maintenance and discontinuation SURMOUNT-4, continue vs placebo switch after lead-in to about 20.9% loss: stopping regained about +14% over 52 weeks while continuing lost a further -5.5%

The advisory panel made the recommendation, which was then approved by director Dr

But Hofseth says these findings remain preliminary which is why he strongly discourages people from taking it as a supplement, as right now, the risks outweigh the benefits

We offer on-site lab testing so we can measure your B12 levels before recommending treatment, because B12 injections are most helpful for people who are actually deficient

A separate 2025 narrative review flagged theoretical concerns about pathologic new blood vessel formation relevant for anyone with cancer history or proliferative conditions