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In fact, much of the progress in tobacco control, most notably in protecting the public from exposure to others smoke by the passage of clean indoor air laws, occurred in the 1970s, 1980s, and 1990slong before the creation in 2014 of 14 mostly university-based centers of excellence in tobacco regulatory science, each given $20 million by the FDA

Mortality-based calculations remain relatively inaccurate as they are subject to a large number of confounders that would have to be properly assessed both from air pollution and tobacco-smoking perspectives and would require a considerable amount of work to be quantified

Prof Jim McManus, president of the Association of Directors of Public Health, said if the government was to implement the recommendations they would "make a huge difference to the nation's health"

But the tobacco industry overturned the ruling in November that year, forcing it to a referendum after obtaining a million signatures

doi:10.3109/15376510903530845