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Establishment of orthotopic CRC model and the CRLM model Male BALB/c mice (aged 68 weeks) and BALB/c nude mice (aged 6 weeks) were obtained from Charles River (Beijing, China) and Qizhen Laboratory Animal Technology Co., Ltd

Glutathione is the bodys main antioxidant

Furthermore, given the distinct expression, regulation and biological roles of various PLA2 family members 60 , it will be interesting to investigate whether ferroptosis suppression contributes to their corresponding biological functions

By enhancing the levels of glutathione in the liver, S-Acetyl-L-glutathione can aid in improving liver function and promoting detoxification processes

Data are presented as mean SD, n = 5 ( b ) biologically independent samples or median SE Median ( d ) calculated as the median abundance of detected lysophospholipid species divided by the median abundance of corresponding phospholipid species for each condition