The combination of GLP-1 and GIP activation is what separates tirzepatide from pure GLP-1 agonists like semaglutide, and clinical data suggests the dual mechanism produces superior weight loss outcomes
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Activity modification: Avoiding overhead or repetitive motions that aggravate symptoms Physical therapy: Focused on restoring scapular control, rotator cuff strength, and posture NSAIDs: Help reduce inflammation and pain during acute flares Corticosteroid injections: Used selectively to control inflammation but may weaken tendons with repeated use Regenerative Treatments and Peptide Therapy For patients who do not respond to conventional therapies, regenerative treatments such as platelet-rich plasma (PRP) and peptides may offer biologic healing without surgery