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One potential problem is that marijuana can interfere with how the body metabolizes Zoloft, which reduces its effectiveness and could lead a doctor to increase the dose if ignorant of the patients marijuana use

The Influence of Substance Use on Adolescent Brain Development

Further work should be performed to examine different fuels, fuel loadings, moisture content, atmospheric conditions (external heat flux, ambient temperature and humidity), wind speeds, cigarette brands, cigarette drawdown length, cigarette orientation relative to the wind, cigarette depth within the fuel bed, etc

J., Ikram, M