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Nicotine replacement therapy remains a recommended option for those seeking to reduce their reliance on smoking while managing nicotine addiction, however it is worth noting that a meta-analysis from Cochrane Library found 'high-certainty' evidence that E-Cigarettes are more effective for quitting smoking than traditional forms of nicotine replacement therapy

While tobacco smoke contains many additional chemicals, each of the compounds tested so far showed successful reductions

Food and Drug Administration 2012: 12)

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The modulation up a minor third to go to the bridge, and the two places where I moves down a minor third employ a principle known as Lenders Rule