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E1011 Labs, Flat Planet, LTD, Glo, BAT, Imperial Brands, IQOS, Philip Morris, iuoc2, Shenzhen Yukan Technology Co., Ltd, KT&G Corp., Mok, Omura, Ploom, and Japan Tobacco International are the leading manufacturers in the cannabis heat-not-burn devices market

[21] In 2025, UK researchers publicly urged a ban on cigarette filters, arguing that filters do not reduce toxicant exposure and contribute to plastic pollution

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Nicotine increases heart rate and blood pressure