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The rates at which individuals metabolize nicotine can vary greatly

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It is a comparator commonly used in tobacco research, which allows the data of a given study to be compared to that of another study

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Nicotine without tobacco, when used in moderation, is not a major health issue, but Im concerned about the need for increasing doses, says Frank Etscorn, Ph.D., professor emeritus at New Mexico Tech and inventor of the nicotine patch in 1986