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Research has repeatedly demonstrated that nicotine, the primary active ingredient in many e-cigarettes, has harmful biochemical impacts on a users brain and body and is extremely addictive

"Social, Environmental, Cognitive, and Genetic Influences on the Use of Tobacco Among Youth", Preventing Tobacco Use Among Youth and Young Adults: A Report of the Surgeon General , Centers for Disease Control and Prevention (US), retrieved 2026-03-26 National Library of Medicine

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The Food and Drug Administration (FDA) on Friday issued six warning letters to manufacturers and retailers for the sale or distribution of unauthorized e-cigarette products promoted at the Total Product Expo industry trade show, a spokesperson for the FDA told CSP