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Outside of that labeled indication, Tesamorelin has been studied for age-related somatopause, non-alcoholic fatty liver disease (NAFLD), mild cognitive impairment and metabolic syndrome

Broad Institute Connectivity Map analysis shows it influences approximately 6% of the human genome making this one of the most broadly active signaling peptides in published research

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Research suggests that the T allele is associated is marked reduction in the activity of the GPx1 enzyme, with some studies showing a 40% reduction in GPx1 activity