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In our laboratory, the effects of the 1 -adrenoceptor antagonist prazosin, the 2 -adrenoceptor agonist clonidine, and the nonselective 1 / 2 -adrenoceptor antagonist propranolol on the elevations in brain reward thresholds associated with nicotine withdrawal was investigated (Bruijnzeel et al., 2010)

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[24] The effects of smoking on periodontal tissues depend on the number of cigarettes smoked daily and the duration of the habit

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