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Due to the side effects linked with these therapeutic agents, including hepatotoxicity, cardiovascular complications, and gastrointestinal lesions, 3050% of patients do not respond effectively to the standard therapies, thereby decreasing the inclusive benefits of the treatment on a long-term basis

J Hepatol

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The appearance of mild-yellowish, mosaic symptoms was associated with a dramatic, 20-fold induction of defense-related genes like PR-1, chitinase and GST (Niehl et al., Potato virus Y (PVY) strains, the aggressive PVY NTN and the mild PVY N (Kogovsek et al., NTN -inoculated leaves displayed chlorotic and/or necrotic ringspot type lesions, while PVY N caused a mild chlorotic ringspot