Similarly, after the death of cells that have experienced ferroptosis, intracellular components are also released in the form of DAMPs upon plasma membrane rupture, triggering the immune system to recruit neutrophils to the injured myocardium (Hu et al., 2021)
Thesis PhD, Saurashtra University Ofoefule SI, Chukwu AN, Anayakoha A, Ebebe IM (2001) Application of Abelmoschus esculentus in solid dosage forms I: use as binder for poorly water-soluble drug
In this sense, the involvement of PKC in experimental models of CIPN was also evidenced by several papers, although mechanical hyperalgesia was decreased by the treatment with PKC inhibitors such as hypericin and calphostin C (Norcini et al., 2009)
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The neurological aspects of the disease are thought to arise from the accumulation of methylmalonyl- CoA due to the requirement of B 12 as a cofactor to the enzyme methylmalonyl-CoA mutase
