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Loss-of-function but not gain-of-function properties of mutant TP53 are critical for the proliferation, survival, and metastasis of a broad range of cancer cells

[4] It was edged out in 1966 by Winston cigarettes, when Pall Mall found that it could no longer compete with the advertising campaign "Winston tastes good like a cigarette should." In the 1940s, Pall Mall had its own grammatically incorrect slogan which touted it as the cigarette which "travels the smoke further", referring to the longer 85 mm length

and Increase the risk of adolescents smoking cigarettes in the future

On average, smokers die 10 years sooner than non-smokers

Camel quickly pivoted to new campaigns based on quality, taste, and health benefits