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While nicotine primordially leads to the release of dopamine, which is a neurotransmitter linked to the activity of the brain and the right side, repeated use of it might result in a downregulation of some systems

doi: 10.1378/chest.15-1858

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There has been a marked reduction in the prevalence of smoking among less advantaged female smokers, decreasing from 29% in 2013 to 14.3% by 2023 despite their economic hardships