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The fundamental pharmacological questioncan a 7,649 Da protein penetrate the scalp in sufficient quantity to reach dermal papilla cellshas not been answered

(2S)-2-Amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Due to its targeted mechanism, Melnotan I has become an important focus in skin biology and pigmentation research