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Smoking is the primary cause of chronic obstructive pulmonary disease (COPD)

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While it is not yet clear what CD45RO expression signifies in terms of ILC functions, it is well-known that in T cells (the adaptive immunity equivalents of ILCs), CD45RO is a marker of activated/memory T cells while CD45RA is expressed on nave T cells 19

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A physician smiling at a pack of cigarettes, a nurse lighting up, a dentist recommending a tobacco brand the advertisements featured in a current National Museum of American History exhibit, "More Doctors Smoke Camels," don't explicitly state that smoking is good for you, but the message is clear