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A randomized controlled trial of progressively reduced nicotine content cigarettes on smoking behaviors, biomarkers of exposure, and subjective ratings

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Prior to sessions, staff placed study cigarettes into existing foil-lined commercial packages and sealed them with a cellophane package wrapper to approximate real world initial use of a novel product

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The practice, commonly used by the tobacco industry, [2] [3] organized crime syndicates and rebel groups, is a form of tax evasion