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2 Smoker's melanosis: the medical name behind the darkening Smoker's melanosis affects an estimated 21 to 31% of regular smokers and develops progressively, with visible pigmentation typically appearing after 3 to 5 years of consistent tobacco use

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Statements Data availability statement The original contributions presented in the study are included in the article/ Supplementary Materials , further inquiries can be directed to the corresponding author

Through his daughter's second marriage, Lorillard was an ancestor of the present Baron Revelstoke and of the heir apparent to the earldom of Oxford and Asquith