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Impressionable teens were a popular target market

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Wax: Wax is extracted from cannabis through butane or hydrocarbon extraction, creating a potent concentrate

TRPV1, on the other hand, has been demonstrated to mediate MC-dependent itch in AD models, and its pharmacological blockade significantly reduces scratching behavior and alleviates local inflammation (90)

Unable to rely on high-profile TV or print spots, tobacco companies pivoted toward digital tobacco marketing and indirect promotion