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Consequently, the amount uptaken by the user depends on hookah use characteristics that are adjusted depending on nicotine levels in tobacco used in order to deliver desired doses [62]

KRT8 high , 46%) (Fig

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In contrast, use of steam-cured chewing tobacco (snus), avoids the carcinogenicity by not generating nitrosamines, but the negative effects of the nicotine on the cardiovascular system and pancreas are not ameliorated