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Reynolds Tobacco Company Date 1942 Source Image from the William Van Duyn Tobacco Advertisement Collection (Ms Coll 20), Medical Historical Library, Harvey Cushing/John Hay Whitney Medical Library, Yale University

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However, smoking negatively impacts arterial health by reducing their ability to contract normally and causing blockages, thus obstructing blood flow

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Over-activation of these cells (by toxic compounds like cigarette smoke, for example) has been shown to trigger an inflammatory response that plays an important role in the initiation and progression of atherosclerosis