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This chapter provides a framework for understanding the broad thrust of developments within DoD by identifying and explaining specific efforts and initiatives

In the case of suspected cobalt hypersensitivity, an intradermal test dose should be administered because anaphylactic shock and death have followed parenteral administration of cyanocobalamin

If nausea is severe enough to prevent adequate nutrition, reduce both compounds to the last tolerated dose and extend the stabilization period before attempting re-escalation

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