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doi:10.1161/CIR.0000000000000107

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Dimensions: 5700 x 3746 px | 48.3 x 31.7 cm | 19 x 12.5 inches | 300dpi Photographer: Uripos More information: Beauty Cigarette Close Up Close Up Closeup Cool Face Female Glossy Gloss Habit Lipstick Mouth People Person Pink Sexy Smoke Smoking Smoker Tip Unlit Vice Woman Women

Overall, these findings demonstrate that chronic smoke exposure promotes the development of a stress-resistant adaptive state that mimics early features of carcinogenesis, characterized by acquired resistance to apoptosis and continuous activation of the NRF2 survival pathway