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Description

Lactate-induced lactylation and cardiometabolic diseases: from epigenetic regulation to therapeutics

The last mechanism is related to the pro-inflammatory effects of CRH and the potential pro-inflammatory properties of arginine vasopressin

JCI Insight 7 , e155899 (2022)

It activates genes linked to collagen production, wound healing, and immune support while suppressing those involved in inflammation and oxidative stress