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Generally, t 1/2 values of peptide drugs range from a few minutes to an hour ( The radioisotope probe assay is a cost-effective and fast method for generating informative data for early preclinical/pharmacokinetic absorption, digestion, metabolism, and excretion studies of biotherapeutics ( Determination of metabolites was the most challenging aspect of this study

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doi: 10.1016/j.stem.2009.09.014

These include modulations in gene expression, stimulation of the endocannabinoid system, and action on the central nervous system

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