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Purity, potency, and consistency are real safety issues, particularly for injectable products. She says that at a minimum, safeguards should include ingredient sourcing, supplier qualification, identity testing, purity, potency, sterility, endotoxin testing, stability, labeling, and adverse event reporting

Other less common reasons include adrenal disorders, thyroid problems, and vitamin deficiencies (specifically vitamin B12 and folic acid)

And retatrutide vs tirzepatide comparisons suggest retatrutide edges ahead by 3 to 5 percentage points at comparable dose levels

Safety and Possible Side Effects Vitamin B12 injections are generally safe when administered correctly