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Because DSIP has not been thoroughly studied in humans, people who are pregnant or breastfeeding, have significant medical conditions, or take multiple medications should avoid using it unless advised by a qualified healthcare professional

J Biomaterials Sci

In Mayo Clinic Proceedings (Vol

While this does not constitute an outright ban, it effectively prohibits its legal use in compounded medications under current FDA regulations

In this review, we specifically focus on the MTHFR polymorphism and related methylation and folate effects on psychiatric diseases as well as the possibility of relationship between clinical phenotypes of MTHFR-related diseases and effectiveness of clinical treatment in psychiatric patients 11