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In M1 macrophages, a low ratio of -KG as a result of glutamine producing succinate can enhance their proinflammatory phenotype, which is beneficial for inhibiting the growth of tumor cells and enhancing their own immune function [24, 28] (Fig

Hospitals with less than 25 percent Medicare utilization and hospitals with 25 to 50 percent Medicare utilization are projected to receive decreases of 3.03 and 1.70 percent, respectively, while hospitals with 50-65 percent and hospitals with greater than 65 percent Medicare utilization are projected to receive increases of 10.54 percent and 1.88 percent, respectively