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The dual action of nicotine makes it unique compared to other stimulants

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We did not observe this effect with the same concentration of nicotine alone in the short-term experiments, but we could observe the dose-dependent inhibitory effect of nicotine on cellular metabolism already at 50 ng/mL and 100 ng/mL in the long-term exposure (21 days)

It permeates hair, skin, clothing, furniture and vehicles