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Application: Hap can be self-administered using a V-shaped self-applicator pipe, known as a Kuripe pipe which connects the mouth to the nostrils

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The nicotine metabolite ratio (NMR), which reflects the ratio of the nicotine metabolites trans-3'-hydroxycotinine to cotinine, is a genetically informed biomarker that has been proven to predict smokers nicotine dependence, likelihood of achieving smoking cessation, and response to various FDA-approved cessation treatments, enabling personalized smoking cessation therapy 6,7

It is essential to make sure that the products meet the intended market's legal and health requirements