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Association of e-cigarette use with quitting did not significantly differ among studies of all smokers using e-cigarettes (irrespective of interest in quitting cigarette-smoking) compared with studies of only smokers interested in cigarette cessation.[14] Similarly, the US National Academy of Sciences, Engineering and Medicine concluded that there is limited evidence that e-cigarettes are effective at promoting smoking cessation

4 As with various other health complications of drug and alcohol misuse, additional factors occurring alongside substance use can impact kidney function