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Hormonal decreases of oestrogen and progesterone possibly deepen the withdrawal syndrome and increase activity of neural circuits associated with craving, Mendrek added

During this phase, teens learn how the substance alters their mood and changes their emotions

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The attempt to apply the 3 Ts (tension, trigger, treatment) model of behavior change proposes that, at a given time, a smoker experiences some degree of motivational tension, which in the presence of a trigger may initiate or enhance quitting [5]