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These tobacco smoking-respiratory findings were supported by multivariable MR analyses accounting for alcohol and cannabis use and abuse, which in addition to the broadly consistent IVW results (within the IVW MR 95% confidence interval but typically less precise) with estimates from the weighted median, weighted mode, and MR Egger sensitivity analyses strengthen causal inference

What About Vaping or Smokeless Tobacco

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By contrast, because initiation of smoking is uncommon after the age of 24 years, 18 a person who reaches 25 years of age as a non-smoker will, on current trends, almost certainly remain a lifelong non-smoker

February 1, 2012