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An analysis of the mechanism reveals that the nanoparticles facilitate the oxidation of GSH into GSSG, leading to disruptions in redox balance and the antioxidant defense system and therefore accumulation of ROS and lipid peroxides

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91 HorsleyL.CummingsJ.MiddletonM.WardT.BackenA.ClampA.et al (2013)

Experimental Protocol 1) Prepare Jurkat cells (110 6 cells/mL in 1640 medium)

Various studies have established a connection between the neuroprotective effects of phenolic compounds and their antioxidative 133 and antiapoptotic properties