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However, in early 2015 a paper appeared in the BMJ which indicated that Chantixs neuropsychiatric adverse effects might be overstated

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On a per puff basis, nicotine yield was similar in research cigarettes (mean = 0.08 mg under the ISO method and 0.25 mg under the CI method) as in small cigars

Patients smoking 1-2 packs or more per day are significantly more likely to have a higher risk of death compared to those who smoke less than one pack per day

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