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More specifically, mitochondrial phagocytosis is activated by hypoxia through the induction of the BNIP3, NIX, and FUNDC1 adaptor proteins, which are localized to the outer mitochondrial membrane and contain a LC3 interaction motif to promote the recruitment of autophagy-associated mechanisms ( Regulation of autophagy during oxidative stress in COPD COPD and oxidative stress COPD is a respiratory disease caused by direct and long-term exposure to toxic particulates or gases

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When products containing synthetic nicotine first came onto the market, some companies claimed that they did not have to be regulated by the Food and Drug Administration (FDA)