rapé tobacco side effects What Nicotine Does to Your Body Nicotiana rustica - Wikipedia

The sensation ranges from mild discomfort to intense pain

After smoking, nicotine quickly enters the bloodstream through the lungs and spreads to the brain, where it binds to the nicotinic acetylcholine receptor (nAChR), which has a high affinity for nicotine, and triggers the release of various neurotransmitters, in particular dopamine

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