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this is not the case with an e-cigarette

Given each SNP is allocated randomly at the time of conception, the MR results should be unconfounded by other factors for clozapine concentration, and therefore they can be thought of as approximately analogous to a series of natural randomized trials evaluating the effect of substance use on the concentration of clozapine

The study operated using random, convenience recruitment (any who wanted to join)

PMID: 32607303 Treb RM, Rezende HD, Gavazzoni Dias MFR

Tobacco smoking is a practice that has been enjoyed for hundreds of years, and to this day, many people continue to take part in it