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Geiss O, Bianchi I, Barrero-Moreno J

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There seems to be a spectrum of nicotine metabolism time that varies by level of female sex hormones, with metabolism times progressing from slower in men, to intermediate in women not on oral contraceptives, to faster in women taking oral contraceptives, Benowitz and colleagues observed

However, with federal regulation of e-cigarettes in place and an uncertain future as many remain under premarket review, some vape shops are now shifting to smoke shops (that sell both vape products and other tobacco products and accessories), diversifying their offerings to include a variety of tobacco products and (un- or under-regulated) cannabis-based products as well as kratom, as well as a growing their online retail segment, which can undermine federal, state and local restrictions on product sales in the retail environment, including youth access

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