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They work best as part of a comprehensive plan that includes proper nutrition and physical activity

Other reported effects include headaches, dizziness, nausea, and gastrointestinal discomfort, though these are less common

If your first B12 test comes back in the "normal" range but you're still having symptoms, asking for MMA and homocysteine tests is a smart and proactive next step

The crystal structure of the hexacarboxylic acid derived from B12 and the molecular structure of the vitamin

It also means allergic reactions are unlikely, though not impossible, since any foreign substance can theoretically trigger sensitivity in susceptible individuals