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In contrast, a cigarette contains thousands of lethal toxins that can prove fatal if used over a long period

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3.2.3 Immunological effects Evidence suggests that e-cigarettes compromise immune function ( In murine models, exposure to e-cigarette vapor significantly impaired pulmonary antimicrobial defenses ( Streptococcus pneumoniae compared with air-exposed controls

If the panel endorsed IQOS, the device would be the first tobacco product marketed under a modified risk claim in the US, suggesting its safer than smoking

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