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However, previous analyses have shown that the indirect estimation by PGW resulted in roughly similar outcomes compared to other indirect estimation techniques [30, 31, 48], so we are confident that our results are broadly reliable

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In contrast, nicotine pouches dont contain tobacco , so cancer risks are dramatically lower (almost on par with regular nicotine gum)

Ethics declarations Competing interests SRP provides consulting services to Moderna and Merck and Co Vaccines, unrelated to the content of this manuscript