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Michaeloudes C, Abubakar-Waziri H, Lakhdar R, Raby K, Dixey P, Adcock IM, et al

Among the most potent NF- B activators are tumour necrosis factor (TNF- ), interleukin (IL)-1 and bacterial lipopolysaccharide (LPS), with TNF- activation being one of the best characterised of the NF- B signalling pathways [200]

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Lys105 is a GSH and enzyme activator in the GSSCys assay In a first set of experiments, we analysed the effects of the Lys105 replacements on the steady-state kinetics at variable GSSCys and GSH concentrations