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10.26355/eurrev_201712_13938 137 VendittiP.Di StefanoL.Di MeoS

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Although we use multiple overlapping models of HNSCC and recapitulate much of the HNSCC biology encountered in the clinical setting ( TP53 wild type vs mutant, HPV-associated vs HPV-independent) we are limited in our ability to precisely model human tobacco exposure in murine models with respect to both time and dose